Hypertension is a common chronic disease with a high global incidence. According to statistics, the current prevalence of adult hypertension in China is 23.2%, with more than 200 million people suffering from the disease. In addition to genetic factors, poor lifestyle and excessive mental stress are important causes of hypertension. In recent years, studies have found that patients with depression-anxiety-associated hypertension are very common in clinical practice, and their treatment effects are not ideal and difficult to treat. This paper reviews the pathogenesis, clinical manifestations, treatment status and comprehensive treatment measures of depression-anxiety-associated hypertension, to provide references for the treatment of depression-anxiety-associated hypertension so that it can be better treated and controlled and the prognosis can be improved. At the same time, it can also further promote the basic and applied research in related fields and improve the clinical diagnosis and treatment plan, to improve the treatment of depressive-anxiety hypertension.