高级检索
当前位置: 首页 > 详情页

Development and validation of a novel nomogram to predict coronary artery calcification: a single center study

文献详情

资源类型:
Pubmed体系:
机构: [1]Department of Orthopedics 2, Hebei Provincial Hospital of Chinese Medicine/The First Affiliated Hospital of Hebei University of Chinese Medicine, Shijiazhuang, China. [2]Department of Cardiology 1, Hebei Provincial Hospital of Chinese Medicine/The First Affiliated Hospital of Hebei University of Chinese Medicine, 389 Zhongshan East Road, Chang'an District, Shijiazhuang City, 050000, Hebei Province, China. [3]Medical Service, Hebei Provincial Hospital of Chinese Medicine/The First Affiliated Hospital of Hebei University of Chinese Medicine, Shijiazhuang, China. [4]Internal Department One, Xinle Hospital of Traditional Chinese Medicine, Shijiazhuang, China.
出处:
ISSN:

关键词: Coronary artery calcification Influencing factors Nomogram TyG Prediction

摘要:
To identify the factors influencing coronary artery calcification (CAC), develop a predictive model for CAC, and evaluate its effectiveness.This retrospective study included 1,526 patients who underwent coronary CT scans at our hospital between January 2020 and October 2024. Patient data included basic demographic information (age, sex, BMI, smoking, alcohol consumption, hypertension, coronary artery disease, hyperlipidemia, diabetes, cerebrovascular disease, etc.) and laboratory test results (TSH, FT4, FT3, LDL, HDL, VLDL, TG, TCHO, etc.). Lasso and logistic regression analyses were conducted to identify significant factors, and a nomogram was developed. The model's performance was evaluated using calibration plots, ROC curves, AUC values, and decision curve analysis (DCA).Univariate analysis showed that the non-calcification group had a longer history of hyperlipidemia and alcohol consumption, and higher triglyceride levels. In the calcification group, patients were older, predominantly male, had higher triglyceride blood glucose index (TyG) levels, and had longer durations of coronary artery disease, hypertension, diabetes, cerebral infarction, and smoking (P< 0.05). Multivariate analysis revealed that age, sex, and the duration of coronary artery disease, hypertension, diabetes, hyperlipidemia, smoking, and alcohol consumption were significantly associated with coronary artery calcification (P< 0.05).This study identified sex, age, and the duration of coronary artery disease, hypertension, diabetes, hyperlipidemia, smoking, and alcohol consumption as key factors influencing coronary artery calcification. The predictive model developed using these factors demonstrated strong predictive performance.© 2025. The Author(s).

基金:
语种:
PubmedID:
中科院(CAS)分区:
出版当年[2026]版:
最新[2025]版:
大类 | 3 区 医学
小类 | 4 区 医学:研究与实验
第一作者:
第一作者机构: [1]Department of Orthopedics 2, Hebei Provincial Hospital of Chinese Medicine/The First Affiliated Hospital of Hebei University of Chinese Medicine, Shijiazhuang, China.
通讯作者:
推荐引用方式(GB/T 7714):
APA:
MLA:

资源点击量:19602 今日访问量:0 总访问量:1147 更新日期:2025-08-01 建议使用谷歌、火狐浏览器 常见问题

版权所有©2020 河北大学附属医院 技术支持:重庆聚合科技有限公司 地址:保定市莲池区裕华东路212号