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Detection of ciprofloxacin and pH by carbon dots and rapid, visual sensing analysis

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机构: [1]College of Chemical and Pharmaceutical Engineering, Hebei University of Science and Technology, Shijiazhuang 050018, China [2]Department of Gynecology, Second Hospital of Hebei Medical University, Shijiazhuang 050000, China [3]Department of Neurosurgery, Second Hospital of Hebei Medical University, Shijiazhuang 050000, China [4]Surgical Department II, The First Affiliated Hospital of Hebei University of Chinese Medicine, Hebei, Provincial Hospital of Chinese Medicine, Shijiazhuang 050000, China [5]Hebei Innovation Center of Pharmaceutical and Chemical Engineering, Hebei University of Science and Technology, Shijiazhuang 050018, China
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关键词: N P-codoped carbon dots Ciprofloxacin detection Fluorescence enhancement Visual detection pH

摘要:
Food safety is a serious issue worldwide and practical detection method is vital for the supervision of food safety. It is necessary to establish efficient and economical methods to detect antibiotics, especially antibiotics in complex systems. This study employs citric acid and m-phenylenediamine to synthesize N, P-codoped carbon dots (N, P-CDs) by a microwave-assisted method. Anhydrous ethanol and phosphoric acid are essential to the properties of N, P-CDs. A "turn-on" fluorescent probe based on N, P-CDs was established for detecting ciprofloxacin (CIP) with detection limit down to 24.2 nm. Semiquantitative test stripe and a PS color detection system for CIP were developed to achieve visual and smart detection. The test stripe is applied to the visual detection of CIP residues in milk and a popular Chinese cuisine, Malatang, for the first time. N, P-CDs can also be used to detect pH in the range of pH 7.5-12.Copyright © 2024 Elsevier Ltd. All rights reserved.

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大类 | 1 区 农林科学
小类 | 1 区 应用化学 1 区 食品科技 1 区 营养学
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第一作者机构: [1]College of Chemical and Pharmaceutical Engineering, Hebei University of Science and Technology, Shijiazhuang 050018, China
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通讯机构: [1]College of Chemical and Pharmaceutical Engineering, Hebei University of Science and Technology, Shijiazhuang 050018, China [5]Hebei Innovation Center of Pharmaceutical and Chemical Engineering, Hebei University of Science and Technology, Shijiazhuang 050018, China
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