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Dual Detection of Norfloxacin and Gatifloxacin by Excitation Tuning Strategy Based on Yellow Carbon Dots

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机构： [1]College of Chemical and Pharmaceutical Engineering, Hebei University of Science and Technology, Shijiazhuang 050018, China [2]Surgical Department II, The First Affiliated Hospital of Hebei University of Chinese Medicine, Hebei Province Hospital of Chinese Medicine, Shijiazhuang 050000, China [3]Department of Gynecology, Second Hospital of Hebei Medical University, Shijiazhuang 050000, China [4]Hebei Research Center of Pharmaceutical and Chemical Engineering, Hebei University of Science and Technology, Shijiazhuang 050018, China [5]Hebei Key Laboratory of Molecular Chemistry for Drug, Hebei University of Science and Technology, Shijiazhuang 050018, China

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关键词： Carbon dots Fluorescence enhancement Detection Norfloxacin Gatifloxacin

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Fluoroquinolones (FQs) are widely used in hospitals, animal husbandry and aquaculture for the treatment of infectious diseases. However, overuse of FQs poses a potential threat to the environment and human. Detection of antibiotics is of great importance in various fields. In this paper, bright yellow fluorescence carbon dots (y-CDs) with quantum yield of 32% were synthesized via a simple and rapid microwave-assisted method using o-phenylenediamine and salicylic acid as raw materials. The fluorescence properties of y-CDs varied under different excitation wavelengths. It is discovered that the excitation wavelength is a critical factor to develop a dual functional fluorescence probe. Under selected excitation wavelength (355 nm), y-CDs can realize dual detection of norfloxacin (NOR) and gatifloxacin (GAT) with good selectivity and high sensitivity in a "turn-on" mode. The detection limits of NOR and GAT are 0.0881 µM and 0.0125 µM, respectively. y-CDs prove practical application in the detection of NOR and GAT in milk and egg samples.© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

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大类 | 3 区化学

小类 | 4 区生化研究方法 4 区分析化学 4 区物理化学

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第一作者机构： [1]College of Chemical and Pharmaceutical Engineering, Hebei University of Science and Technology, Shijiazhuang 050018, China

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通讯机构： [1]College of Chemical and Pharmaceutical Engineering, Hebei University of Science and Technology, Shijiazhuang 050018, China [4]Hebei Research Center of Pharmaceutical and Chemical Engineering, Hebei University of Science and Technology, Shijiazhuang 050018, China [5]Hebei Key Laboratory of Molecular Chemistry for Drug, Hebei University of Science and Technology, Shijiazhuang 050018, China

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Dual Detection of Norfloxacin and Gatifloxacin by Excitation Tuning Strategy Based on Yellow Carbon Dots

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