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Computational model-based hemodynamic comparisons of traditional and modified idealized models of autologous radiocephalic fistula

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机构: [1]School of Quality and Technical Supervision, Hebei University, Baoding, Hebei, China [2]Ultrasonography Department, Baoding No.1 Central Hospital, Baoding, Hebei, China [3]Affiliated Hospital of Hebei University/ School of Clinical Medicine, Hebei University, Baoding, Hebei, China
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关键词: autologous arteriovenous fistula computational fluid dynamics hemodynamics model modification

摘要:
Autologous arteriovenous fistula (AVF) is a commonly used vascular access (VA) for hemodialysis, and hemodynamic changes are one of the main factors for its failure. To explore the effect of geometry on the hemodynamics in the AVF, a modified model is built with a gradual and smooth turn at the anastomosis and is compared with the traditional model, which has an abrupt sharp turn at the anastomisis. Transient computational fluid dynamics (CFD) simulations were performed for the comparison and analysis of the hemodynamic fields of the two models at different stages of the pulse cycle. The results showed that the low shear stress region and high oscillatory shear stress region in the modified AVF model coincided with regions of intimal hyperplasia that have been identified by previous studies. A comparison with the blood flow velocities measured in vivo was performed, and the error between the simulation results and the medical data was reduced by 22% in the modified model, which verifies the rationality and utility of the modified model. A modified autologous arteriovenous fistula model with a gradual and smooth turn at the anastomosis is constructed in comparison to the traditional model. Transient computational fluid dynamics simulations were conducted to compare the hemodynamics between the two models. The modified model exhibits good agreement with previous studies in terms of low shear stress distribution and high oscillatory shear stress distribution. The error between the simulation results and the in vivo measured data was reduced by 22% in the modified model. image

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大类 | 4 区 医学
小类 | 2 区 数学与计算生物学 3 区 数学跨学科应用 4 区 工程:生物医学
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Q2 MATHEMATICAL & COMPUTATIONAL BIOLOGY Q2 MATHEMATICS, INTERDISCIPLINARY APPLICATIONS Q3 ENGINEERING, BIOMEDICAL

影响因子: 最新[2023版] 最新五年平均 出版当年[2024版] 出版当年五年平均 出版前一年[2023版]

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第一作者机构: [1]School of Quality and Technical Supervision, Hebei University, Baoding, Hebei, China
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通讯机构: [1]School of Quality and Technical Supervision, Hebei University, Baoding, Hebei, China [2]Ultrasonography Department, Baoding No.1 Central Hospital, Baoding, Hebei, China
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