Abstract: Objective: To explore the value of an auxiliary band for endoscopic surgery in endoscopic submucosal dissection of colorectal lateral developmental tumors, with a view to providing a new method for the early diagnosis and treatment of such tumors, and thus improving the prognosis of patients. Methods: The clinical data of 60 patients who underwent endoscopic submucosal dissection of colorectal LST in the hospital between June 2022 and June 2024 were retrospectively analyzed. The patients were categorized into the auxiliary belt group (n = 30) and the control group (n =30) according to whether or not the auxiliary belt for endoscopic surgery was used during the operation. The operation time, the number of intraoperative hemostasis, the number of titanium clips used, the success rate of ESD, the incidence of postoperative complications, the length of hospitalization and the hospitalization cost of the two groups were compared.Results: The operation time of the patients in the auxiliary belt group was slightly longer than that of the control group,but the difference was not statistically significant (P > 0.05); the number of intraoperative hemostasis and the number of titanium clips used in the auxiliary belt group was less than that of the control group, but the difference was not statistically significant (P > 0.05); the success rate of ESD in the auxiliary belt group was 93.33%, which was higher than that of the control group, which was 90.00%. The ESD success rate in the auxiliary belt group was 93.33%, which was higher than the ESD success rate of 90.00% in the control group, but the difference was not statistically significant (P >0.05); the incidence of postoperative complications in the auxiliary belt group was lower than that in the control group,but the difference was not statistically significant (P > 0.05); the length of hospital stay in the auxiliary belt group was significantly shorter than that of the control group, and the difference was statistically significant (P < 0.05); and the hospitalization cost of patients in both groups was comparable, with no significant difference (P > 0.05). Conclusion: The auxiliary belt for endoscopic surgery has certain application value in endoscopic submucosal dissection of colorectal lateral developmental tumors, which can assist the surgical operation, may reduce intraoperative bleeding and the use of titanium clips, shorten the patient’s hospitalization time, and does not increase the hospitalization cost.