Background: Primary liver tumors can be a serious threat to life and health. Early diagnosis may be life saving. Therefore, enhancing the accuracy of non-invasive early detection of liver tumors is imperative. Methods: Firstly, image enhancement was applied to augment the dataset, resulting in a total of 464 samples after employing seven data augmentation methods. Subsequently, the XGBoost model was utilized to construct and learn the mapping relationship between Computed Tomography (CT) and corresponding hyperspectral imaging (HSI) data. This model enables the prediction of HSI features corresponding to CT features, thereby enriching CT with more comprehensive hyperspectral information.Results: Four classifiers were employed to discern the presence of tumors in patients. The results demonstrated exceptional performance, with a classification accuracy exceeding 90%.Conclusions: This study proposes an artificial intelligence-based methodology that utilizes early CT radiomics features to predict HSI features. Subsequently, the results are utilized for non-invasive tumor prediction and early screening, thereby enhancing the accuracy of non-invasive liver tumor detection.