机构:[1]Postdoctoral Research Station of Neurosurgery,Affiliated Hospital of Hebei University,Hebei University,China河北大学附属医院[2]Department of Neurosurgery,Affiliated Hospital of Hebei University,Hebei University,China河北大学附属医院重点学科神经外科[3]Key Laboratory of Precise Diagnosis and Treatment of Glioma in Hebei Province,Affiliated Hospital of Hebei University,Hebei University,China河北大学附属医院[4]Department of Neurology,Affiliated Hospital of Hebei University,Hebei University,China河北大学附属医院[5]Department of Pathology,Affiliated Hospital of Hebei University,Hebei University,China河北大学附属医院[6]Department of Neurosurgery, General Hospital of Ningxia Medical University, Ningxia Medical University, China
Following spinal cord injury (SCI), the central nervous system undergoes significant reconstruction. The dynamic change in the interaction of the brain-spinal cord axis as well as in structure-function relations plays a vital role in the determination of neurological functions, which might have important clinical implications for the treatment and its efficacy evaluation of patients with SCI. Brain connectomes based on neuroimaging data is a relatively new field of research that maps the brain's large-scale structural and functional networks at rest. Importantly, increasing evidence shows that such resting-state signals can also be seen in the spinal cord. In the present review, we focus on the reconstruction of multi-level neural circuits after SCI. We also describe how the connectome concept could further our understanding of neuroplasticity after SCI. We propose that mapping the cortical-subcortical-spinal cord networks can provide novel insights into the pathologies of SCI.
基金:
Start-Up research grants of Affiliated Hospital of Hebei University [31010413]; Key Research Projects of Ningxia Hui Autonomous Region of China [2018BCG01002]; Hebei Natural Science Foundation Precision Medicine Joint Project [H2020201206]; Hebei provincial the central government-guided local science and technology development fund project [216Z7711G]
第一作者机构:[1]Postdoctoral Research Station of Neurosurgery,Affiliated Hospital of Hebei University,Hebei University,China[2]Department of Neurosurgery,Affiliated Hospital of Hebei University,Hebei University,China[3]Key Laboratory of Precise Diagnosis and Treatment of Glioma in Hebei Province,Affiliated Hospital of Hebei University,Hebei University,China
共同第一作者:
通讯作者:
通讯机构:[1]Postdoctoral Research Station of Neurosurgery,Affiliated Hospital of Hebei University,Hebei University,China[2]Department of Neurosurgery,Affiliated Hospital of Hebei University,Hebei University,China[3]Key Laboratory of Precise Diagnosis and Treatment of Glioma in Hebei Province,Affiliated Hospital of Hebei University,Hebei University,China[5]Department of Pathology,Affiliated Hospital of Hebei University,Hebei University,China[*1]Department of Neurosurgery,Affiliated Hospital of Hebei University,Hebei University,Baoding,071000,Hebei,China[*2]Department of Pathology,Affiliated Hospital of Hebei University,Hebei University,Baoding,071000,Hebei,China.
推荐引用方式(GB/T 7714):
Zhang Lijian,Wang Luxuan,Xia Hechun,et al.Connectomic mapping of brain-spinal cord neural networks: Future directions in assessing spinal cord injury at rest[J].NEUROSCIENCE RESEARCH.2022,176:9-17.doi:10.1016/j.neures.2021.10.008.
APA:
Zhang, Lijian,Wang, Luxuan,Xia, Hechun,Tan, Yanli,Li, Chunhui&Fang, Chuan.(2022).Connectomic mapping of brain-spinal cord neural networks: Future directions in assessing spinal cord injury at rest.NEUROSCIENCE RESEARCH,176,
MLA:
Zhang, Lijian,et al."Connectomic mapping of brain-spinal cord neural networks: Future directions in assessing spinal cord injury at rest".NEUROSCIENCE RESEARCH 176.(2022):9-17