Long non-coding RNA RMST serves as a diagnostic biomarker in patients with carotid artery stenosis and predicts the occurrence of cerebral ischemic event: A retrospective study
机构：[1]Pre-hospital Emergency Center, The First Hospital of Hebei Medical University, Shijiazhuang, China.[2]Department of Interventional Vascular Surgery, Affiliated Hospital of Hebei University, Baoding, China.河北大学附属医院
The purpose of this retrospective study is to explore the diagnostic and prognostic roles of serum RMST in carotid artery stenosis (CAS).Serum levels of RMST were detected in CAS patients, and the relationship between degree of carotid stenosis and RMST levels was analyzed. The ROC curve was drawn to evaluate RMST value in predicting the risk of CAS. Then, all CAS patients received a 5-year follow-up. K-M curve was used to analyze the significance of RMST on prognosis of CAS patients. Multi-factor cox logistic regression analysis was conducted to evaluate independent factors for outcome of CAS patients.An increased RMST expression was certified in CAS patients when compared with healthy controls. The increase of serum RMST expression was related to high degree of carotid stenosis. In addition, serum RMST was a possible diagnosis and an independent influencing factor of prognosis in patients with CAS.Raised serum RMST level was found in patients with CAS. Detecting RMST expression levels was of high value for predicting the occurrence and outcomes in CAS.
基金：
The author(s) disclosed receipt of the following financial support
for the research, authorship, and/or publication of this article: This
work was supported by the project "Therapeutic effect of carotid
endarterectomy on patients with arterial stenosis and its impact on
cranial nerve injury"[No. 20220391].
第一作者机构：[1]Pre-hospital Emergency Center, The First Hospital of Hebei Medical University, Shijiazhuang, China.
通讯作者：
通讯机构：[2]Department of Interventional Vascular Surgery, Affiliated Hospital of Hebei University, Baoding, China.[*1]Department of Interventional Vascular Surgery, Affiliated Hospital of Hebei University, No. 212 Yuhua East Road, Baoding 071000, China.
推荐引用方式(GB/T 7714)：
Wang Cui,Zhao Feng,He Yunliang,et al.Long non-coding RNA RMST serves as a diagnostic biomarker in patients with carotid artery stenosis and predicts the occurrence of cerebral ischemic event: A retrospective study[J].Vascular.2023,31(5):908-913.doi:10.1177/17085381221100095.
APA：
Wang Cui,Zhao Feng,He Yunliang,E Yajun&Li Shanfeng.(2023).Long non-coding RNA RMST serves as a diagnostic biomarker in patients with carotid artery stenosis and predicts the occurrence of cerebral ischemic event: A retrospective study.Vascular,31,(5)
MLA：
Wang Cui,et al."Long non-coding RNA RMST serves as a diagnostic biomarker in patients with carotid artery stenosis and predicts the occurrence of cerebral ischemic event: A retrospective study".Vascular 31..5(2023):908-913
