In this study, Zn-SiC nanoparticles (NPs) were fabricated by a simple approach using Zn NPs loaded onto silicon carbide (SiC). The functional groups, crystalline behavior, morphological construction, and elemental compositions of the synthesized NPs were characterized and confirmed by various methods such as ultraviolet-visible spectroscopy, X-ray diffraction analysis, Fourier-transform infrared spectroscopy, transmission electron microscopy, energy dispersive X-ray mapping, and dynamic light scattering analysis. The cell viability results indicated that the Zn NPs loaded onto SiC NPs exhibited high biocompatibility and low toxicity. Further, the cell viability was assessed by optical microscopy. The wound healing rates of SiC and Zn-SiC NPs were 82% and 96%, respectively, at the end of 14 d, which were higher than that of the control sample. These results strongly support the possibility of using these Zn NPs loaded onto SiC NPs as a promising wound healing agent for osteoporotic and healthy bone formation in femoral fractures.
第一作者机构：[1]Hebei Univ, Affiliated Hosp, Dept Orthoped, Baoding 710000, Hebei, Peoples R China
通讯作者：
推荐引用方式(GB/T 7714)：
Gao Fei,Guo Zhao,Zhang Bin,et al.A synergic fabrication of Zn-SiC composite coatings for the osteoporotic and healthy bone formation in femoral fractures[J].MATERIALS EXPRESS.2021,11(3):336-343.doi:10.1166/mex.2021.1915.
APA：
Gao, Fei,Guo, Zhao,Zhang, Bin,Ma, Xiaoyong,Li, Ying&Li, Congjie.(2021).A synergic fabrication of Zn-SiC composite coatings for the osteoporotic and healthy bone formation in femoral fractures.MATERIALS EXPRESS,11,(3)
MLA：
Gao, Fei,et al."A synergic fabrication of Zn-SiC composite coatings for the osteoporotic and healthy bone formation in femoral fractures".MATERIALS EXPRESS 11..3(2021):336-343
