Objective: To quantitatively analyze distribution characteristics of sweat gland nerve fibres (SGNF) in normal Chinese individuals for obtaining a reference for early diagnosis of peripheral neuropathy. Patients and methods: Skin biopsy samples were collected from 192 normal Chinese individuals and divided into six, four and two groups according to anatomic sites, age and gender, respectively. SGNF morphology was observed and SGNF density (SGNFD) was determined. Results: There was a significant difference in SGNFD among different anatomic sites, age and gender. A degressive tendency was observed from proximal to distal anatomic sites. SGNFD was the lowest in subjects in the 21-40-year-old age group, but was the highest in subjects in the > 61-year-old age group. Overall, SGNFD fluctuated with age. SGNFD in males was significantly higher than that in females. Conclusions: Distribution characteristics of SGNF in normal individuals may serve as a reference for early diagnosis of nerve fibre damage.
基金：
Natural Sciences Fund of Hebei Province [H2013201255]; Project of Finance Department of Hebei Province [361007-3]
第一作者机构：[1]Hebei Univ, Dept Neurol, Affiliated Hosp, Baoding 071000, Hebei, Peoples R China
共同第一作者：
通讯作者：
通讯机构：[5]Hebei Univ, Dept Orthoped, Affiliated Hosp, 212 Yuhua East Rd, Baoding 071000, Hebei, Peoples R China[*1]Department of Orthopedics, Affiliated Hospital of Hebei University, No. 212 Yuhua East Road, Baoding, 071000, Hebei, China
推荐引用方式(GB/T 7714)：
Ling Li,Liu Yongdan,Sun Yifei,et al.Distribution characteristics of sweat gland nerve fibres in normal humans identified by acetylcholinesterase histochemical staining[J].CLINICAL NEUROLOGY AND NEUROSURGERY.2020,189:doi:10.1016/j.clineuro.2019.105620.
APA：
Ling, Li,Liu, Yongdan,Sun, Yifei,Cai, Yun,Jiang, Ye...&Xue, Jinwei.(2020).Distribution characteristics of sweat gland nerve fibres in normal humans identified by acetylcholinesterase histochemical staining.CLINICAL NEUROLOGY AND NEUROSURGERY,189,
MLA：
Ling, Li,et al."Distribution characteristics of sweat gland nerve fibres in normal humans identified by acetylcholinesterase histochemical staining".CLINICAL NEUROLOGY AND NEUROSURGERY 189.(2020)
