This paper aims to disclose the details on the generation and trapping of microbubbles in water induced by self-focused femtosecond laser. For this purpose, high-speed cameras and a high frequency ultrasonic imager were adopted to monitor the entire process of microbubble generation and trapping. The experimental results show that a single microbubble generated in laser-induced optical breakdown (LIOB) can be trapped stably in water by a self-focused femtosecond laser. Furthermore, the author discussed the physical features of microbubbles generated and trapped by the said femtosecond laser. The research results lay a solid basis for the application of microbubbles in targeted therapy at the molecular level.
基金：
National Natural Science Foundation of China [11104058]; National Basic Research Program of China [2011 CB707500]; Natural Science Foundation of Hebei Province [A2011201155]; Major Scientific Instruments Program of Ministry of Science and Technology of China [201IYQ03011405]; Hebei Provincial Education Department [ZD2015044]; Key research and development plan of Ministry of Science and Technology of China [2016YFC0104203]
第一作者机构：[1]Hebei Univ, Coll Qual & Tech Supervis, Baoding 071002, Peoples R China
通讯作者：
通讯机构：[2]Tianjin Med Univ, Gen Hosp, Dept Gastroenterol, Tianjin 300052, Peoples R China[3]Hebei Univ, Affiliated Hosp, Dept Gastroenterol, Baoding 071000, Peoples R China
推荐引用方式(GB/T 7714)：
Yang Kun,Xue Linyan,Yin Kang,et al.Microbubble generation and trapping induced by femtosecond laser and acoustic signal analysis[J].TRAITEMENT DU SIGNAL.2017,34(1-2):33-44.doi:10.3166/TS.34.33-44.
APA：
Yang, Kun,Xue, Linyan,Yin, Kang,Liu, Shuang&Meng, Jie.(2017).Microbubble generation and trapping induced by femtosecond laser and acoustic signal analysis.TRAITEMENT DU SIGNAL,34,(1-2)
MLA：
Yang, Kun,et al."Microbubble generation and trapping induced by femtosecond laser and acoustic signal analysis".TRAITEMENT DU SIGNAL 34..1-2(2017):33-44
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