The relationship between hip fracture risk and opioid use remains controversial. Thus, we performed a meta-analysis to assess the risk of hip fracture among opioid users. PubMed and EMBASE were searched for studies published from the inception of the databases until June 2015. The information was extracted independently by two teams of authors. When the heterogeneity was significant, the random-effects model was used to calculate the overall pooled risk estimates. Ten studies with 697,011 patients were included in the final meta-analysis. The overall combined relative risk for the use of opioids and hip fracture was 1.54 [95 % confidence interval (CI) 1.34-1.77]. Subgroup analyses revealed sources of heterogeneity, and sensitivity analysis indicated stable results, and no publication bias was observed. This meta-analysis demonstrates that opioids significantly increase the risk of hip fracture.
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外文
被引次数：
WOS：
PubmedID：
中科院(CAS)分区：
出版当年[2018]版：
大类|3 区医学
小类|4 区内分泌学与代谢4 区医学：研究与实验
最新[2025]版：
大类|4 区医学
小类|4 区内分泌学与代谢4 区医学：研究与实验
JCR分区：
出版当年[2017]版：
Q3MEDICINE, RESEARCH & EXPERIMENTALQ3ENDOCRINOLOGY & METABOLISM
最新[2023]版：
Q3ENDOCRINOLOGY & METABOLISMQ3MEDICINE, RESEARCH & EXPERIMENTAL
第一作者机构：[1]Hebei Univ Engn, Affiliated Hosp, Dept Operating Room, Handan, Peoples R China
通讯作者：
推荐引用方式(GB/T 7714)：
Ping Fumin,Wang Ying,Wang Jing,et al.Opioids increase hip fracture risk: a meta-analysis[J].JOURNAL OF BONE AND MINERAL METABOLISM.2017,35(3):289-297.doi:10.1007/s00774-016-0755-x.
APA：
Ping, Fumin,Wang, Ying,Wang, Jing,Chen, Jie,Zhang, Wenxian...&Liu, Yugang.(2017).Opioids increase hip fracture risk: a meta-analysis.JOURNAL OF BONE AND MINERAL METABOLISM,35,(3)
MLA：
Ping, Fumin,et al."Opioids increase hip fracture risk: a meta-analysis".JOURNAL OF BONE AND MINERAL METABOLISM 35..3(2017):289-297
