The researchers aimed in highlighting the correlations of serum MMP-9, TIMP-1, TGF-beta 1 and bFGF levels with atrial fibrillation (AF) within diseased persons showing no structural heart ailment. A total of 236 eligible diseased persons had been categorized within AF category (n=168) and non-AF category (n=68). Left atrial diameter (LAD), left ventricular end-diastolic dimension (LVEDD) and left ventricular ejection fraction (LVEF) had been measured through cardiac ultrasonography. Comparing concerning non-AF category, AF class had larger LAD and smaller LVEF (P<0.01). MMP-9 and TGF-beta 1 levels had been higher while TIMP-1 level remained less within AF class as compared to non-AF class (P<0.01). Age, LVEF and left atrial MMP-9/TIMP-1 remained free correlative factors of AF (P<0.01). MMP-9/TIMP-1 remained definitely correlated concerning LAD within AF class (r=0.509, P<0.01). Left atrial MMP-9/TIMP-1 remained higher within diseased persons regarding persistent AF (P<0.01). Left atrial MMP-9/TIMP-1 is correlated with AF within diseased persons having no structural heart ailment, particularly in the case of persistent AF.
第一作者机构:[1]Capital Med Univ, Beijing Chaoyang Hosp, Dept Cardiol, Beijing 100000, Peoples R China[2]Shijiazhuang Peoples Hosp, Dept Cardiol, Shijiazhuang 050000, Hebei, Peoples R China
通讯作者:
推荐引用方式(GB/T 7714):
Chen Hao,Zhang Fang,Zhang Yuanli,et al.Correlations of Serum MMP-9, TIMP-1, TGF-β and bFGF Levels with Atrial Fibrillation in Patients without Structural Heart Disease[J].INTERNATIONAL JOURNAL OF HUMAN GENETICS.2021,21(2):55-60.doi:10.31901/24566330/21.2.774.
APA:
Chen, Hao,Zhang, Fang,Zhang, Yuanli&Yang, Xinchun.(2021).Correlations of Serum MMP-9, TIMP-1, TGF-β and bFGF Levels with Atrial Fibrillation in Patients without Structural Heart Disease.INTERNATIONAL JOURNAL OF HUMAN GENETICS,21,(2)
MLA:
Chen, Hao,et al."Correlations of Serum MMP-9, TIMP-1, TGF-β and bFGF Levels with Atrial Fibrillation in Patients without Structural Heart Disease".INTERNATIONAL JOURNAL OF HUMAN GENETICS 21..2(2021):55-60