研究单位:[1]Beijing InnoCare Pharma Tech Co., Ltd.[2]The First Affiliated Hospital of Anhui Medical University,Hefei,Anhui,China,230022[3]The Second Affiliated Hospital of Wannan Medical College,Wuhu,Anhui,China,241000[4]Beijing Chao-Yang Hospital,Capital Medical University,Beijing,Beijing,China,100020[5]Beijing Friendship Hospital, Capital Medical University,Beijing,Beijing,China,100050[6]Peking University Third Hospital,Beijing,Beijing,China,100191[7]Beijing Tongren Hospital,CMU,Beijing,Beijing,China,100730[8]The First Affiliated Hospital of Chongqing Medical University,Chongqing,Chongqing,China,400016[9]Chongqing Traditional Chinese Medicine Hospital,Chongqing,Chongqing,China,400021[10]Fujian Medical University Union Hospital,Fuzhou,Fujian,China,350001[11]The First Affiliated Hospital of Fujian Medical University,Fuzhou,Fujian,China,350005[12]Dermatology Hospital of Southern Medical University,Guangzhou,Guangdong,China,510091[13]Sun Yat-sen Memorial Hospital, Sun Yat-sen University,Guangzhou,Guangdong,China,510120[14]The Second Affiliated Hospital of Guangzhou Medical University,Guangzhou,Guangdong,China,510120[15]Liuzhou People''s Hospital,Liuzhou,Guangxi,China,545006[16]The Affiliated Hospital of Guizhou Medical University,Guiyang,Guizhou,China,550001[17]Affiliated Hospital of Chengde Medical University,Chengde,Hebei,China,067000[18]Affiliated Hospital of Hebei University of Engineering,Handan,Hebei,China,056000[19]The Second Hospital of Hebei Medical University,Shijiazhuang,Hebei,China,050000[20]The 2nd Affiliated Hospital of Harbin Medical University,Harbin,Heilongjiang,China,150001[21]The Second Affiliated Hospital of Henan University of Science and technology,Luoyang,Henan,China,471000[22]Nanyang Central Hospital,Nanyang,Henan,China,473000[23]Sanmenxia Central Hospital,Sanmenxia,Henan,China,472000[24]Henan Provincial People''s Hospital,Zhengzhou,Henan,China,450003[25]Jingzhou Central Hospital,Jingzhou,Hubei,China,434020[26]Wuhan Hospital Of Traditional Chinese and Western Medicine (Wuhan No.1 Hospital),Wuhan,Hubei,China,430022[27]Xiangya Hospital of Central South University,Changsha,Hunan,China,410008[28]The Affiliated Hospital of Inner Mongolia Medical University,Hohhot,Inner Mongolia,China,010030[29]The First People''s Hospital of Changzhou,Changzhou,Jiangsu,China,213003[30]The First People''s Hospital of Lianyungang,Lianyungang,Jiangsu,China,222002[31]Hospital for skin diseases,Institute of dermatology chinese academy of medical sciences,peking union medical college,Nanjing,Jiangsu,China,210042[32]First Affiliated Hospital of Gannan Medical University,Ganzhou,Jiangxi,China,341000[33]Dermatology Hospital of Jiangxi Province,Nanchang,Jiangxi,China,330000[34]The First Hospital of Jilin University,Changchun,Jilin,China,130021[35]Northeast International Hospital,Shenyang,Liaoning,China,110000[36]Qilu Hospital of Shandong University,Jinan,Shandong,China,250012[37]Shandong First Medical University Affiliated Dermatology Hospital,Jinan,Shandong,China,250022[38]The Affiliated Hospital of Qingdao University,Qingdao,Shandong,China,266000[39]Huashan Hospital, Fudan University,Shanghai,Shanghai,China,200040[40]Shanghai Skin Disease Hospital skin Disease of tongji University,Shanghai,Shanghai,China,200443[41]Taiyuan Central Hospital,Taiyuan,Shanxi,China,030009[42]The First Affiliated Hospital of Xi''an Jiaotong University,Xi''an,Shanxi,China,710061[43]The Second Affiliated Hospital of Xi''an Jiaotong University,Xi''an,Shanxi,China,710114[44]Chengdu Second People''s Hospital,Chengdu,Sichuan,China,610017[45]Sichuan Provincial People''s Hospital,Chengdu,Sichuan,China,610072[46]Tianjin Academy of Traditional Chinese Medicine Affiliated Hospital,Tianjin,Tianjin,China,300120[47]The First Affiliated Hospital of Kunming Medical University,Kunming,Yunnan,China,650032[48]The Second Affiliated Hospital Zhejiang University School of Medicine,Hangzhou,Zhejiang,China,310009[49]The Fourth Affiliated Hospital, Zhejiang University School of Medicine,Jinhua,Zhejiang,China,322000[50]The First Affiliated Hospital Of Ningbo University,Ningbo,Zhejiang,China,315000[51]The 1st School of Medicine,School of information and Engineering The 1st Affiliated Hospital of WMU,Wenzhou,Zhejiang,China,325000
研究目的:
This is a multicenter, randomized, double-blind, placebo-controlled Phase III clinical study to evaluate the efficacy, safety, PK characteristics of ICP-488 in Chinese adults with moderate to severe plaque psoriasis.