研究单位：[1]Peking University First Hospital,Beijing,Beijing,China,100034[2]Peking University Third Hospital[3]Dongzhimen Hospital, Beijing[4]Beijing Hospital[5]Beijing Boai Hospital[6]Peking University Shenzhen Hospital[7]First Affiliated Hospital of Guangxi Medical University[8]Guizhou Provincial People's Hospital[9]First Affiliated Hospital of Chengdu Medical College[10]Affiliated Hospital of Hebei University[11]The Second Hospital of Hebei Medical University[12]The First Affiliated Hospital of Zhengzhou University[13]the Affiliated Hospital of Hubei Traditional Chinese Medical College[14]Xiangya Hospital of Central South University[15]The First Affiliated Hospital with Nanjing Medical University[16]The First Affiliated Hospital of Dalian Medical University[17]Chifeng Second Hospital[18]The First Affiliated Hospital of BaoTou Medical College[19]Qilu Hospital of Shandong University[20]Shandong Provincial Hospital[21]Qianfoshan Hospital[22]Second Hospital of Shanxi Medical University[23]Minhang Central Hospital[24]West China Hospital[25]Sichuan Provincial People's Hospital[26]Tianjin Medical University General Hospital[27]Tianjin Medical University Second Hospital[28]the First Affiliated Hospital of the Medical College of Shihezi University[29]First Affiliated Hospital of Xinjiang Medical University[30]The Second Affiliated Hospital of Kunming Medical University[31]Yuxi City People's Hospital[32]Zhejiang University[33]Xinqiao Hospital of Chongqing[34]The Second Affiliated Hospital of Chongqing Medical University[35]First Affiliated Hospital of Chongqing Medical University[36]The Second Hospital of Anhui Medical University[37]The First Affiliated Hospital of Anhui Medical University[38]General Hospital of Ningxia Medical University[39]Shengjing Hospital
This study aimed to explore underlying mechanisms of chronic kidney disease progression and its association with adverse consequences. It will enroll approximately 5000 pre-dialysis chronic kidney disease patients aged between 18 and 74 years in mainland China and follow-up for at least 5 years. Questionnaires, anthropometric measures, laboratory tests, and biomaterials will be collected at baseline and annually. The principal clinical outcomes of the study consist of renal disease events, cardiovascular events, and death.
