Effect of Concurrent Capecitabine-based Long-term Radiotherapy Followed by XELOX Plus TME in Patients With High Risk Rectal Cancer: a Multi-centers, Randomized Controlled, Open-Label Trial
研究单位:[1]Peking University People's Hospital[2]Peking University Cancer Hospital & Institute[3]Beijing Friendship Hospital[4]Peking Union Medical College Hospital[5]Chinese PLA General Hospital[6]Shanghai Zhongshan Hospital[7]Fujian Medical University Union Hospital[8]Nanfang Hospital, Southern Medical University[9]Xijing Hospital[10]Hebei Medical University Fourth Hospital[11]Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University[12]Affiliated Hospital of Hebei University[13]Peking University People's Hospital,Beijing,Beijing,China,100044[14]Beijing Friendship Hospital,Beijing,Beijing,China
The purpose of this study was to evaluate the effect of concurrent capecitabine-based long-term radiotherapy followed by 4 cycles XELOX pre- a delayed TME compared with 6 cycles XELOX post- a Regular Timing TME in patients with high-risk rectal cancer defined by MRI.