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Effect of Concurrent Capecitabine-based Long-term Radiotherapy Followed by XELOX Plus TME in Patients With High Risk Rectal Cancer: a Multi-centers, Randomized Controlled, Open-Label Trial

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研究单位: [1]Peking University People's Hospital [2]Peking University Cancer Hospital & Institute [3]Beijing Friendship Hospital [4]Peking Union Medical College Hospital [5]Chinese PLA General Hospital [6]Shanghai Zhongshan Hospital [7]Fujian Medical University Union Hospital [8]Nanfang Hospital, Southern Medical University [9]Xijing Hospital [10]Hebei Medical University Fourth Hospital [11]Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University [12]Affiliated Hospital of Hebei University [13]Peking University People's Hospital,Beijing,Beijing,China,100044 [14]Beijing Friendship Hospital,Beijing,Beijing,China

关键词: High Risk Rectal Cancer Total neoadjuvant chemoradiotherapy Lengthening interval between radiotherapy and surgery

研究目的:
The purpose of this study was to evaluate the effect of concurrent capecitabine-based long-term radiotherapy followed by 4 cycles XELOX pre- a delayed TME compared with 6 cycles XELOX post- a Regular Timing TME in patients with high-risk rectal cancer defined by MRI.

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