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Dexmedetomidine Supplemented Analgesia and Incidence of Postoperative Delirium

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研究单位: [1]Peking University First Hospital,Beijing,Beijing,China,100034 [2]Affiliated Hospital of Hebei University [3]Qingdao Municipal Hospital [4]The Second Affiliated Hospital of Air Force Medical University [5]Peking University International Hospital [6]Guizhou Provincial People's Hospital [7]The Third Xiangya Hospital of Central South University [8]Shanxi Provincial Cancer Hospital [9]Tianjin Hospital of ITCWM-Nankai Hospital [10]Zhongda Hospital [11]Chongqing University Fuling Hospital

关键词: elderly surgery analgesia dexmedetomidine delirium

研究目的:
Delirium is a frequently occurred cerebral complication in elderly patients after surgery, and its occurrence is associated with worse outcomes. Sleep disturbances is considered to be one of the most important risk factors of postoperative delirium. Previous studies showed that, for elderly patients admitted to the ICU after surgery, low-dose dexmedetomidine infusion improved the quality of sleep and decreased the incidence of delirium. The investigators hypothesize that, for elderly patients after cancer surgery, dexmedetomidine supplemented analgesia can also decrease the incidence of delirium, possibly by improving sleep quality. The purpose of this multicenter, randomized controlled trial is to investigate the impact of dexmedetomidine supplemented analgesia on the incidence of delirium in elderly patients after cancer surgery.

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