研究单位:[1]Peking University First Hospital,Beijing,Beijing,China,100034[2]Affiliated Hospital of Hebei University[3]Qingdao Municipal Hospital[4]The Second Affiliated Hospital of Air Force Medical University[5]Beijing Chao Yang Hospital[6]Beijing Shijitan Hospital, Capital Medical University[7]Beijing Tsinghua Chang Gung Hospital[8]Peking University International Hospital[9]Beijing Ditan Hospital[10]Guizhou Provincial People's Hospital[11]The Third Xiangya Hospital of Central South University[12]Shanxi Provincial Cancer Hospital[13]Tianjin Hospital of ITCWM-Nankai Hospital[14]Zhongda Hospital
A majority of the elderly patients undergo surgery for malignant tumors. For these patients, postoperative tumor recurrence and metastasis are main factors that worsen long-term outcomes. The investigators hypothesize that dexmedetomidine supplemented analgesia in elderly patients after cancer surgery may help to maintain immune function and improve long-term outcomes, possibly by relieving stress and inflammatory response, improving analgesic efficacy and sleep quality, and reducing delirium incidence.