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Dexmedetomidine Supplemented Analgesia and Long-term Survival After Cancer Surgery

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研究单位: [1]Peking University First Hospital,Beijing,Beijing,China,100034 [2]Affiliated Hospital of Hebei University [3]Qingdao Municipal Hospital [4]The Second Affiliated Hospital of Air Force Medical University [5]Beijing Chao Yang Hospital [6]Beijing Shijitan Hospital, Capital Medical University [7]Beijing Tsinghua Chang Gung Hospital [8]Peking University International Hospital [9]Beijing Ditan Hospital [10]Guizhou Provincial People's Hospital [11]The Third Xiangya Hospital of Central South University [12]Shanxi Provincial Cancer Hospital [13]Tianjin Hospital of ITCWM-Nankai Hospital [14]Zhongda Hospital

关键词: Elderly Surgery Analgesia Dexmedetomidine Long-term outcome

研究目的:
A majority of the elderly patients undergo surgery for malignant tumors. For these patients, postoperative tumor recurrence and metastasis are main factors that worsen long-term outcomes. The investigators hypothesize that dexmedetomidine supplemented analgesia in elderly patients after cancer surgery may help to maintain immune function and improve long-term outcomes, possibly by relieving stress and inflammatory response, improving analgesic efficacy and sleep quality, and reducing delirium incidence.

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