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Association of dyslipidaemia with osteoporosis in postmenopausal women

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收录情况: ◇ SCIE ◇ 预警期刊

机构: [1]Department of Vasculocardiology,The Affiliated Hospital of Hebei University,Baoding,Hebei,China [2]Department of Gastrointestinal Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China [3]Department of Orthopaedics, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China [4]Department of Orthopaedics,The Affiliated Hospital of Hebei University,Baoding,Hebei,China [5]Department of Neurosurgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China
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关键词: Dyslipidaemia osteoporosis diabetes low-density lipoprotein high-density lipoprotein bone mineral density cholesterol

摘要:
Objective To assess the association of dyslipidaemia with osteoporosis in postmenopausal women. Methods Data from 160 postmenopausal women with newly diagnosed osteoporosis (osteoporosis group) and 156 healthy controls (control group) were retrospectively reviewed from 2016 to 2020. The primary outcomes were laboratory values assessed by a multivariate binary logistic regression model. Results Factors that greatly increased the risk of being in the osteoporosis group included high low-density lipoprotein (LDL) and low high-density lipoprotein (HDL) levels. The osteoporosis group had lower HDL and higher LDL levels than the control group. A multivariate binary logistic regression model showed that lower HDL and higher LDL levels were the only variables that were significantly associated with osteoporosis (odds ratio 1.86, 95% confidence interval: 3.66-4.25 and odds ratio 1.47, 95% confidence interval: 1.25-2.74, respectively). Conclusion Low HDL and high LDL levels may be associated with the occurrence of osteoporosis in postmenopausal women.

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出版当年[2022]版:
大类 | 4 区 医学
小类 | 4 区 药学 4 区 医学:研究与实验
最新[2025]版:
大类 | 4 区 医学
小类 | 4 区 医学:研究与实验 4 区 药学
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出版当年[2021]版:
Q4 MEDICINE, RESEARCH & EXPERIMENTAL Q4 PHARMACOLOGY & PHARMACY
最新[2023]版:
Q4 MEDICINE, RESEARCH & EXPERIMENTAL Q4 PHARMACOLOGY & PHARMACY

影响因子: 最新[2023版] 最新五年平均 出版当年[2021版] 出版当年五年平均 出版前一年[2020版] 出版后一年[2022版]

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第一作者机构: [1]Department of Vasculocardiology,The Affiliated Hospital of Hebei University,Baoding,Hebei,China
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通讯机构: [3]Department of Orthopaedics, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China [4]Department of Orthopaedics,The Affiliated Hospital of Hebei University,Baoding,Hebei,China [5]Department of Neurosurgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China [*1]Department of Orthopaedics,The Affiliated Hospital of Hebei University,Yuhua East Road No. 212 Baoding,Hebei 071000,China.Department of Orthopaedics,The First Affiliated Hospital,Sun Yat-sen University,No. 58 Zhongshan 2nd Road,Yuexiu District,Guangzhou,510080,China.Department of Neurosurgery,The First Affiliated Hospital,Sun Yat-sen University,No. 58 Zhongshan 2nd Road,Yuexiu District,Guangzhou,510080,China.
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