机构:[1]Department of Vasculocardiology,The Affiliated Hospital of Hebei University,Baoding,Hebei,China河北大学附属医院[2]Department of Gastrointestinal Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China中山大学附属第一医院[3]Department of Orthopaedics, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China中山大学附属第一医院[4]Department of Orthopaedics,The Affiliated Hospital of Hebei University,Baoding,Hebei,China河北大学附属医院[5]Department of Neurosurgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China中山大学附属第一医院
Objective To assess the association of dyslipidaemia with osteoporosis in postmenopausal women. Methods Data from 160 postmenopausal women with newly diagnosed osteoporosis (osteoporosis group) and 156 healthy controls (control group) were retrospectively reviewed from 2016 to 2020. The primary outcomes were laboratory values assessed by a multivariate binary logistic regression model. Results Factors that greatly increased the risk of being in the osteoporosis group included high low-density lipoprotein (LDL) and low high-density lipoprotein (HDL) levels. The osteoporosis group had lower HDL and higher LDL levels than the control group. A multivariate binary logistic regression model showed that lower HDL and higher LDL levels were the only variables that were significantly associated with osteoporosis (odds ratio 1.86, 95% confidence interval: 3.66-4.25 and odds ratio 1.47, 95% confidence interval: 1.25-2.74, respectively). Conclusion Low HDL and high LDL levels may be associated with the occurrence of osteoporosis in postmenopausal women.
基金:
Hebei
Province 2019 Medical Science Research
Project Plan (Grant No. 20190934).
语种:
外文
被引次数:
WOS:
PubmedID:
中科院(CAS)分区:
出版当年[2022]版:
大类|4 区医学
小类|4 区药学4 区医学:研究与实验
最新[2025]版:
大类|4 区医学
小类|4 区医学:研究与实验4 区药学
JCR分区:
出版当年[2021]版:
Q4MEDICINE, RESEARCH & EXPERIMENTALQ4PHARMACOLOGY & PHARMACY
最新[2023]版:
Q4MEDICINE, RESEARCH & EXPERIMENTALQ4PHARMACOLOGY & PHARMACY
第一作者机构:[1]Department of Vasculocardiology,The Affiliated Hospital of Hebei University,Baoding,Hebei,China
共同第一作者:
通讯作者:
通讯机构:[3]Department of Orthopaedics, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China[4]Department of Orthopaedics,The Affiliated Hospital of Hebei University,Baoding,Hebei,China[5]Department of Neurosurgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China[*1]Department of Orthopaedics,The Affiliated Hospital of Hebei University,Yuhua East Road No. 212 Baoding,Hebei 071000,China.Department of Orthopaedics,The First Affiliated Hospital,Sun Yat-sen University,No. 58 Zhongshan 2nd Road,Yuexiu District,Guangzhou,510080,China.Department of Neurosurgery,The First Affiliated Hospital,Sun Yat-sen University,No. 58 Zhongshan 2nd Road,Yuexiu District,Guangzhou,510080,China.
推荐引用方式(GB/T 7714):
Zhang Lingnan,Liu Qilong,Zeng Xianshang,et al.Association of dyslipidaemia with osteoporosis in postmenopausal women[J].JOURNAL OF INTERNATIONAL MEDICAL RESEARCH.2021,49(3):doi:10.1177/0300060521999555.
APA:
Zhang, Lingnan,Liu, Qilong,Zeng, Xianshang,Gao, Wenshan,Niu, Yanan...&Xu, Guixing.(2021).Association of dyslipidaemia with osteoporosis in postmenopausal women.JOURNAL OF INTERNATIONAL MEDICAL RESEARCH,49,(3)
MLA:
Zhang, Lingnan,et al."Association of dyslipidaemia with osteoporosis in postmenopausal women".JOURNAL OF INTERNATIONAL MEDICAL RESEARCH 49..3(2021)