Photothermal ablation therapy (PTA) has been widely reported; however, it is not possible to predict the internal temperature of the tumor in real time that causes ineffective treatment and normal tissue burns. Here, we have designed a photothermal therapy strategy under real-time temperature monitoring by injecting gold nanorods (AuNRs) and NaYF4: Yb3+/Er3+ into the tumor site where AuNRs are used for PTA of cancer cells by converting the absorbed energy into heat and using Yb3+ , Er3+-NaYF4 phosphors to monitor the temperature inside the tumor. Our experiments confirm the effectiveness of this strategy, which is expected to be an aid in the development of real-time temperature monitoring and effective photothermal therapy for the treatment of cancers.
基金：
National Natural Science Foundation of China (NSFC) [11974097, 51872095]; Hebei Province Department of Education Fund [A20192010732]; Hebei Province Natural Science Fund [A2015201192]; Key Technology R&D Program of Hebei province Baoding City [15ZG044, 15ZG045]; Key Technology R&D Program of Hebei province Boarding City [15ZG044, 15ZG045]; UT Arlington
第一作者机构：[1]Hebei Univ, Coll Phys Sci & Technol, Hebei Hosp, Inst Anim Care & Use Comm, Baoding 071002, Peoples R China
通讯作者：
推荐引用方式(GB/T 7714)：
Shen Wenzeng,Zhang Xuefeng,Liu Dongyang,et al.A Photothermal Therapy Strategy for Monitoring Real-Time Temperature in Kidney Cancers by Injecting Gold Nanorods with Phosphors[J].JOURNAL OF BIOMEDICAL NANOTECHNOLOGY.2021,17(3):501-508.doi:10.1166/jbn.2021.3009.
APA：
Shen, Wenzeng,Zhang, Xuefeng,Liu, Dongyang,Xing, Christina,Tucker, Isabelle...&Yang, Yanmin.(2021).A Photothermal Therapy Strategy for Monitoring Real-Time Temperature in Kidney Cancers by Injecting Gold Nanorods with Phosphors.JOURNAL OF BIOMEDICAL NANOTECHNOLOGY,17,(3)
MLA：
Shen, Wenzeng,et al."A Photothermal Therapy Strategy for Monitoring Real-Time Temperature in Kidney Cancers by Injecting Gold Nanorods with Phosphors".JOURNAL OF BIOMEDICAL NANOTECHNOLOGY 17..3(2021):501-508
