机构：[1]Hebei Univ Chinese Med, Dept Radiotherapy, Hebei Prov Hosp Chinese Med, Shijiazhuang 050011, Hebei, Peoples R China[2]Hebei Univ Chinese Med, Hebei Prov Hosp Chinese Med, Dept Med Adm, Shijiazhuang 050011, Hebei, Peoples R China[3]Natl Univ Def Technol, Coll Elect Countermeasure, Hefei 230037, Peoples R China
This systematic review and meta-analysis investigated the prognostic value of paraneoplastic dermatomyositis on the survival of patients with nasopharyngeal carcinoma (NPC). The combined hazard ratio (HR) is 1.43 [95% confidence interval (CI):0.98-2.10, p:0.06]. There was a decreased 3-year survival in NPC cases with dermatomyositis [ risk ratio (RR) : 0.86, 95% CI:0.74-1.01, p: 0.07; risk difference (RD):-0.11, 95% CI:-0.22-0.01, p:0.06] although it was not significantly associated with 5-year survival (RR: 0.89, 95% CI:0.71-1.13, p: 0.34; RD:0.06, 95% CI:- 0.19-0.07, p:0.34). All reported NPC cases accompanying paraneoplastic syndrome were type II non-keratinising carcinomas.
基金：
Hebei Province Key Research and Development (RD) Project [19277770D]; Natural Science Foundation of Hebei Province [H2018423026]; Foundation of Health and Family Planning Commission of Hebei [20180686, 20180688]
