Objective center dot To investigate the value of Doppler ultrasound in evaluating the efficacy of diabetic retinopathy. Methods center dot A retrospective analysis was conducted on 90 hospitalized patients with type 2 diabetes from January 2019 to January 2020. The patients were divided into two groups: 34 cases without retinopathy and 56 cases with diabetic retinopathy. Clinical data and Doppler ultrasonography results were collected and analyzed to evaluate the value of Doppler ultrasound. Results center dot After treatment, various indicators, including blood glucose, HbA(1c), FPG, 2hFPG, HOMA-IR, and FINS, showed significant improvement in both groups (P < .05). There was no significant difference before and after treatment (P > .05). Before treatment, the retinopathy group exhibited significantly different central artery parameters: PSA (8.35 +/- 1.08), EDV (5.80 +/- 0.62), RI (1.53 +/- 0.25), compared to patients without retinopathy: PSA (13.61 +/- 1.80), EDV (7.23 +/- 0.51), RI (0.85 +/- 0.02) (t = 12.019, 11.631, 11.461, P =.01, .01, .00), respectively. After treatment, the central artery parameters improved in both groups. The retinopathy group showed PSA (10.44 +/- 0.26), EDV (6.84 +/- 0.85), RI (1.01 +/- 0.04), while patients without retinopathy exhibited PSA (15.13 +/- 1.20), EDV (8.50 +/- 0.80), RI (0.71 +/- 0.08) (t = 15.94, 12.01, 13.32, P =.01, .01, .01), respectively. Similarly, before treatment, the retinopathy group had different central artery parameters: PSA (30.35 +/- 5.15), EDV (8.85 +/- 1.67), RI (1.53 +/- 0.25), compared to patients without retinopathy: PSA (34.41 +/- 5.20), EDV (11.34 +/- 2.56), RI (0.88 +/- 0.15) (t = 12.108, 11.542, 11.57, P =.01, .01, .01), respectively. After treatment, the central artery parameters improved in both groups. The retinopathy group showed PSA (33.26 +/- 4.27), EDV (9.37 +/- 1.86), RI (0.98 +/- 0.35), while patients without retinopathy exhibited PSA (36.15 +/- 4.24), EDV (13.51 +/- 2.13), RI (0.76 +/- 0.23) (t = 13.84, 12.14, 10.11, P =.01, .01, .01), respectively. Conclusions center dot Color Doppler ultrasound monitoring of fundus hemodynamic parameters can accurately reflect the changes in blood vessels in diabetic eyes. It provides real-time and objective evaluation of fundus hemodynamic indexes. This technology demonstrates high repeatability and simple operation, making it valuable for the non-invasive detection of early retinopathy.