The determination of carcinoembryonic antigen (CEA) has been an hot topic in the medical analysis due to the positive correlation between its elevation and many cancers. How to detect CEA with high sensitivity and speed has therefore been of great interest in analytical chemistry. Electrochemical analytical techniques have been considered well suited for screening specific molecules due to their high sensitivity and rapidity. This review summarizes the advances in electrochemical analytical techniques for CEA detection. We divided the electrochemical sensor into impedance, amperage, voltammetry, potentiometry, electrogenerated chemiluminescence (ECL), and photoelectrochemical (PEC). We presented their primary methodologies and important works in them separately. In addition, we compared the performance of recently published sensors through a table. Finally, we present perspectives on this topic based on the review.
基金：
specific project of the national cancer center of China on the scientific research of oncology [NCC2017A24, SPRY4-lT1]
第一作者机构：[1]Hebei Med Univ, Hosp 4, Dept Thorac Surg, Shijiazhuang 05000, Hebei, Peoples R China[2]Xingtai Peoples Hosp, Dept Thorac Surg, Xingtai 054000, Hebei, Peoples R China
通讯作者：
推荐引用方式(GB/T 7714)：
Wang Haijun,Guo Qiang,Wang Mingbo,et al.Advances in detection of carcinoembryonic antigen for diagnosis of esophageal cancer based on electrochemical aptamer sensors[J].INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE.2022,17(10):doi:10.20964/2022.10.59.
APA：
Wang, Haijun,Guo, Qiang,Wang, Mingbo,Liu, Changjiang&Tian, Ziqiang.(2022).Advances in detection of carcinoembryonic antigen for diagnosis of esophageal cancer based on electrochemical aptamer sensors.INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE,17,(10)
MLA：
Wang, Haijun,et al."Advances in detection of carcinoembryonic antigen for diagnosis of esophageal cancer based on electrochemical aptamer sensors".INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE 17..10(2022)
