Hybrid hydrogels based on poly(N-isopropylacrylamide) and poly(acrylamide) containing CdTe quantum dots with UV sensitive response and including NaYF4:Yb/Er nanoparticles have been prepared through glow discharge electrolysis plasma. The fluorescence characteristic and temperature sensitivity of the prepared hydrogels have been most extensively studied. In addition, scanning electron microscopy, X-ray diffraction, differential scanning calorimetry were determined to characterize the morphology, degree of crystallinity and the phase transformations of the hydrogels. The results suggested that the phase transition temperature of the hydrogels was 32.5 degrees C and the hydrogels had good up-conversion and down-conversion fluorescence properties. Moreover, hybrid hydrogels had a reversible temperature response performance.