OBJECTIVE: To analyze the changes of adiponection (ANP) and matrix metalloproteinase-9 (MMP-9) in patients with coronary heart diseases (CHD) of different types, to investigate the correlation between these changes and stability of coronary artery plague. METHODS: Inpatients of our hospital were divided into 56 cases with acute myocardial infarction (AMI), 56 cases with unstable angina pectoris (UA), 54 cases with stable angina pectoris (SA), and 60 cases with CHD excluded by using coronary arteriongraphy as the control group. Changes of ANP and MMP-9 were determined, and the correlation was analyzed. RESULTS: 1. ANP and MMP-9 levels in CHD group were higher than those of control group (P < 0.01). 2. Serum ANP and MMP-9 levels in AMI and UA groups were significantly higher than those in control group and SA group (P < 0.05). 3. MMP-9 level in AMI group was significantly higher than that in UA group (P < 0.01). CONCLUSION: 1. Increased ANP and MMP-9 levels are the independent risk factors of CHD; 2. Increased levels of ANP and MMP-9 in patients with CHD suggest instability of atherosclerotic plaque.
语种：
外文
被引次数：
WOS：
PubmedID：
中科院(CAS)分区：
出版当年[2016]版：
大类|4 区医学
小类|4 区工程：生物医学4 区卫生保健与服务
最新[2025]版：
大类|4 区医学
小类|4 区工程：生物医学4 区卫生保健与服务
JCR分区：
出版当年[2015]版：
Q4HEALTH CARE SCIENCES & SERVICESQ4ENGINEERING, BIOMEDICAL
最新[2023]版：
Q3HEALTH CARE SCIENCES & SERVICESQ4ENGINEERING, BIOMEDICAL
第一作者机构：[1]Hebei Univ, Affiliated Hosp, Baoding 071000, Hebei, Peoples R China
推荐引用方式(GB/T 7714)：
Li Ya.Correlation analysis of levels of adiponectin and matrix metalloproteinase-9 with stability of coronary heart disease[J].TECHNOLOGY AND HEALTH CARE.2015,23:S95-S98.doi:10.3233/THC-150937.
APA：
Li, Ya.(2015).Correlation analysis of levels of adiponectin and matrix metalloproteinase-9 with stability of coronary heart disease.TECHNOLOGY AND HEALTH CARE,23,
MLA：
Li, Ya."Correlation analysis of levels of adiponectin and matrix metalloproteinase-9 with stability of coronary heart disease".TECHNOLOGY AND HEALTH CARE 23.(2015):S95-S98
